Quantitative analysis of PRA1-LIR intensity in wt and rd1 retinas. The intensity of the PRA1-like immunofluorescent signal in wt (blue) and rd1 (orange) was determined for the IS region (A) and the inner plexiform layer (B). PRA1-LIR was less intense in the IS layer of rd1 retinas when compared to age-matched wt retinas at all time points, although variability precluded significance at P6. In contrast, the average intensity of PRA1-LIR was very similar in wt and rd1 retinas with some difference seen only at P8. *p < 0.05, **p < 0.01.
Dickison et al. BMC Neuroscience 2012 13:152 doi:10.1186/1471-2202-13-152