Comparison of the mechanical response threshold of Aβ-fiber neurons to application of von Frey filaments to the peripheral receptive fields of control and neuropathic rats. The column on the left shows the mean mechanical response thresholds of GF, RA, SA, MS and HTM neurons in control (oen bars) and neuropathic (NeP; filled bars) rats. Note that the activation threshold of MS neurons was significantly lower in neuropathic than in control animals. The column on the right shows the distribution of the mechanical activation thresholds of the individual neurons. There is a leftward shift in the distribution of the SA and MS neurons in the neuropathic animals compared with the control animals. **P < 0.01. Unpaired t-test.
Zhu and Henry BMC Neuroscience 2012 13:15 doi:10.1186/1471-2202-13-15