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Functional crosstalk in culture between macrophages and trigeminal sensory neurons of a mouse genetic model of migraine

Alessia Franceschini14, Asha Nair1, Tanja Bele3, Arn MJM van den Maagdenberg2, Andrea Nistri1* and Elsa Fabbretti13

Author Affiliations

1 Department of Neuroscience and Italian Institute of Technology Unit, International School for Advanced Studies (SISSA), Via Bonomea 265, Trieste, 34136, Italy

2 Departments of Human Genetics & Neurology, Leiden University Medical Centre, Leiden, RC, 2300, The Netherlands

3 Center for Biomedical Sciences and Engineering, University of Nova Gorica, Nova Gorica, SI-5000, Slovenia

4 Present address: Department of Experimental and Diagnostic Medicine, Section of General Pathology, University of Ferrara, Ferrara, Italy

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BMC Neuroscience 2012, 13:143  doi:10.1186/1471-2202-13-143

Published: 21 November 2012

Additional files

Additional file 1:

Figure S1. Macrophage microspheres phagocytosis activity. Histograms quantifies the fluorescence values (arbitrary units; AU) of microspheres latex FITC-conjugated beads phagocytosis in peritoneal macrophage cultures (MФ., or trigeminal WT or KI cultures alone or in macrophage-neuronal co-cultures (WT+MФ and KI+MФ) n = 3, * p < 0.05; ** p < 0.01.

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