Table 1

Plasma glucose, insulin and triglyceride concentrations, calculated HOMA index and whole blood ß-hydroxybutyrate concentrations at 4 and 8 weeks of feeding control or high-sucrose diet
4 weeks 8 weeks
Parameter Control High-sucrose Control High-sucrose Time Diet Time x Diet
Glucose (mmol/L) 4.0 ± 0.41 4.4 ± 0.1 4.1 ± 1.0 6.0 ± 1.8*** <0.05 <0.01
Insulin (ng/ml) 0.6 ± 0.4 0.3 ± 0.1 0.7 ± 0.3 1.8 ± 0.9** <0.001 <0.05
HOMA1 index 2.3 ±1.91 1.4 ± 0.41 4.1 ± 4.1 10.5 ± 4.8** <0.001 <0.05 <0.05
Triglycerides (mg/ml) 0.9 ± 0.2 0.7 ± 0.2 0.7 ± 0.3 1.5 ± 0.5** <0.05 <0.05 <0.01
β-hydroxybutyrate (mmol/L) 0.9 ± 0.2 0.9 ± 0.2 0.6 ± 0.2 0.7 ± 0.11 <0.05

Values are means ± SD (n = 8) 1n=7 due to insufficient sample. 1n=7 due to insufficient sample. Data were analyzed by two-way repeated measures ANOVA, followed by a one-way ANOVA and Bonferroni’s post-hoc test comparing high-sucrose versus controls at 4 and 8 weeks. **p < 0.01; ***p < 0.001 indicates significant difference compared to 8-week control mean.

Taha et al.

Taha et al. BMC Neuroscience 2012 13:131   doi:10.1186/1471-2202-13-131

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