Open Access Highly Accessed Research article

MicroRNA expression profile of the hippocampus in a rat model of temporal lobe epilepsy and miR-34a-targeted neuroprotection against hippocampal neurone cell apoptosis post-status epilepticus

Kai Hu1, Yuan-Yuan Xie1, Chen Zhang2, Dong-Sheng Ouyang3, Hong-Yu Long1, Dan-Ni Sun1, Li-Li Long1, Li Feng1, Yi Li1 and Bo Xiao1*

Author Affiliations

1 Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P. R. China

2 Department of Neurology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, P. R. China

3 Institute of Clinical Pharmacology, Central South University, Changsha, Hunan, 410078, P. R. China

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BMC Neuroscience 2012, 13:115  doi:10.1186/1471-2202-13-115

Published: 22 September 2012

Additional files

Additional file 1:

Study design, sample size and animal allocation. The experiments, grouping design, sample size and animal number for statistical analyses are detailed in this file.

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Additional file 2:

Agilent Rat miRNA microarray scanned images. The 12 Agilent Rat miRNA microarray scanned images are shown in this file.

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Additional file 3:

Agilent Rat miRNA microarray raw data. The 12 Agilent Rat miRNA microarray raw data are shown in this file.

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Additional file 4:

The KEGG pathway analysis results. The significantly enriched pathways of deregulated miRNA targets, as predicted by the KEGG pathway database, are shown in this file.

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