Effect of dietary α-tocopherol supplementation on chemosensory and motor function in senior animals. A. Examples of extracellular recording of afferents in the superior lip nerve before and after application of n-amyl acetate (4 ppm) of senior animals with dietary supplementation of vehicle only (− αTocopherol; top trace) or α-tocopherol (+ αTocopherol; bottom trace). B. Average action potential frequency (bin size 30 sec) of afferents in superior lip nerve 4 minutes before and 2 minutes during amyl acetate application. There is no difference in response upon n-amyl acetate application between the two different treatment groups C. Average change in the number of rasps evoked by application of pond water (DS) or sucrose (0.4%). Only sucrose induced a robust but similar response in senior animals fed with dietary supplementation of vehicle only (− αTocopherol) or α-tocopherol (+ αTocopherol).
Watson et al. BMC Neuroscience 2012 13:103 doi:10.1186/1471-2202-13-103