Schematic of a DIV-BBB module. A bundle of porous polypropylene hollow fibers is suspended in the DIV-BBB chamber. The artificial capillaries are in continuity with a medium source through a flow path consisting of gas-permeable silicon tubing. Ports positioned on either side of the module allow access to the luminal and abluminal compartments. Note how this artificial capillary system closely mimics the physiology of the BBB in situ.
Hossain et al. BMC Neuroscience 2011 12:92 doi:10.1186/1471-2202-12-92