Figure 3.

Spreading and migration speeds of TG G93A and TG WT microglia. (A) Speed of spreading (μm²/s) of NTG (WT), TG WT, NTG (G93A) and TG G93A microglia, n = three TG WT mice (12 cells) and three NTG (WT) mice (ten cells) obtained from two litters, and ten TG G93A mice (15 cells) and nine NTG (G93A) mice (20 cells) from four litters. (B) Speed of migration (μm/min) of NTG (WT), TG WT, NTG (G93A) and TG G93A microglia on genotype-matched astrocytic monolayers. Data are mean ± SEM; Student's t test, *** p = 0.0004 versus NTG (WT) microglia, n = three TG WT mice (ten cells) and three NTG (WT) mice (ten cells) from two litters.