Table 3

Classification of the top ten up- and down-regulated transcripts in the ears of Danio rerio allowed to recover for four days following acoustic overexposure compared to two days.

Gene ID

Description (gene symbol) [homologous organism]

Fold change

P-value

GO Process or Function


NM_194425

major histocompatibility complex class I ZE gene (mhc1ze)

34.36

0.0143

Immunity

NM_001004628

zgc:101740 (zgc:101740)

6.82

0.0099

Nucleic acid metabolism

AF273879

immunoglobulin heavy variable 2-2 (ighv2-2)

4.54

0.0437

Undetermined

NM_001004587

zgc:92214 (zgc:92214)

4.17

0.0116

Metal ion binding

AB062116

heat shock cognate 70-kd protein (hsp70)

3.30

0.0029

Response to heat

BC074056

zgc:153863 (zgc:153863)

2.61

0.0191

Undetermined

NM_001007378

PTC7 protein phosphatase homolog [S. cerevisiae] (pptc7)

2.49

0.0452

Catalytic activity

NM_131108

type I cytokeratin (cki)

2.27

0.0099

Structural molecule

NM_001003445

zgc:92533 (zgc:92533)

2.25

0.0146

Undetermined

BC059568

zgc:73226 (zgc:73226)

2.17

0.0282

Regulation of apoptosis

AI721910

1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta) (agpat4)

-2.73

0.0384

Metabolic process

NM_001007365

troponin I, skeletal, fast 2a.1 (tnni2a.1)

-2.73

0.0305

Undetermined

NM_213556

jun B proto-oncogene (junb)

-2.81

0.0478

Transcription regualtion

AF500198

fibronectin 1b (fn1b)

-2.89

0.0481

Undetermined

NM_212837

potassium voltage-gated channel, subfamily H (eag-related), member 2 (kcnh2)

-3.01

0.0411

Signal transduction, transcription, ion transport

NM_200091

signal transducer and activator of transcription 1b (stat1b)

-3.11

0.0308

Transcription, transduction

NM_198815

stearoyl-CoA desaturase (delta-9-desaturase) (scd)

-3.29

0.0374

Lipid biosynthesis

NM_201334

zgc:64065 (zgc:64065)

-3.69

0.0053

Intracellular signalling

NM_170767

vitellogenin 1 (vtg1) (replaced by NM_001044897)

-4.25

0.0203

Chemical stimulus response

AY286447

growth hormone 1 (gh1)

-11.78

0.0025

Hormone activity


Schuck et al. BMC Neuroscience 2011 12:88   doi:10.1186/1471-2202-12-88

Open Data