Table 2

Classification of the top ten up- and down-regulated transcripts in the ears of Danio rerio allowed to recover for four days following acoustic overexposure compared to controls.

Gene ID

Description (gene symbol) [homologous organism]

Fold change

P-value

GO Process or Function


NM_205623

luteinizing hormone beta 1 (lhbeta1)

10.70

0.0012

Undetermined

AF273879

immunoglobulin heavy variable 2-2 (ighv2-2)

10.17

0.0167

Undetermined

NM_205729

nuclear receptor subfamily 1, group d, member 1 (nr1d1)

8.33

0.0002

Transcription

BC085676

si:ch211-284a13.1 (Chst15)

7.54

0.0022

Undetermined

NM_205687

glycoprotein hormones, alpha polypeptide (cga)

7.02

0.0305

Hormone activity

NM_181438

proopiomelanocortin a (pomca)

6.95

0.0039

Neuropeptide signaling pathway

AY286447

growth hormone 1 (gh1)

5.47

0.0044

Hormone activity

NM_212439

period homolog 1b [Drosophila] (per1b)

4.24

0.0010

Transcription

BC054944

transferrin-a (tfa)

2.79

0.0003

Iron ion transport

NM_200634

amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein (apbb1ip)

2.68

0.0106

Signal transduction

NM_001002085

slow-specific troponin C (stnnc)

-3.26

0.0011

Calcium ion binding

BC045465

matrilin 1 (matn1)

-3.27

0.0027

Undetermined

NM_001002119

zgc:86810 (zgc:86810)

-3.45

0.0096

Undetermined

NM_131591

actin, alpha 1, skeletal muscle (acta1)

-3.45

0.0030

ATP/Nucleotide/Protein binding

NM_201095

zgc:56376 (zgc:56376)

-3.61

0.0421

Metal ion binding

NM_200965

ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a (atp2a2a)

-4.16

0.0004

Regulation of cation transport, ATP biosynthetic process

NM_205676

zgc:77592 (zgc:77592)

-5.50

0.0052

Undetermined

NM_170767

vitellogenin 1 (vtg1)

-13.29

0.0067

Lipid transport

AF425742

slow myosin heavy chain 1, like (smyhc1l)

-33.26

0.0190

Stress response, contraction

NM_200516

atrial myosin light chain (zgc:66286)

-62.03

0.0026

Calcium ion binding


Schuck et al. BMC Neuroscience 2011 12:88   doi:10.1186/1471-2202-12-88

Open Data