Table 1

Classification of the top ten up- and down-regulated transcripts in the ears of Danio rerio allowed to recover for two days following acoustic overexposure compared to controls.

Gene ID

Description (gene symbol)

Fold change

P-value

GO Process or Function


AY286447

growth hormone 1 (gh1)

64.43

0.0002

Hormone activity

NM_205623

luteinizing hormone beta 1 (lhbeta1)

10.10

0.0003

Undetermined

NM_205729

nuclear receptor subfamily 1, group D, member 1 (nr1d1)

9.32

0.0002

Transcription

NM_205687

glycoprotein hormones, alpha polypeptide (cga)

7.38

0.0083

Hormone activity

BC085676

si:ch211-284a13.1 (Chst15)

6.43

0.0003

Undetermined

NM_198815

stearoyl-CoA desaturase (delta-9-desaturase) (scd)

5.35

0.0027

Lipid metabolism

NM_181438

proopiomelanocortin (pomc)

5.02

0.0015

Signal transduction

AW419856

zebrafish gridded kidney wu:fj84d10

4.62

0.0006

Undetermined

NM_212889

zgc:77076 (zgc:77076)

4.31

0.0002

Signal transduction

NM_201334

zgc:64065 (zgc:64065)

4.07

0.0006

Signal transduction

NM_212439

period homolog 4 (per4)

3.86

0.0005

Signal transduction

NM_205676

zgc:77592 (zgc:77592)

-3.45

0.0018

Undetermined

NM_001002085

slow-specific troponin C (stnnc)

-3.71

0.0004

Calcium ion binding

NM_001004628

zgc:101740 (zgc:101740)

-4.66

0.0048

Nucleoside metabolic process

NM_200965

ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a (atp2a2a)

-5.31

0.0002

Calcium ion binding

NM_001004112

zgc:92375 (zgc:92375)

-5.47

0.0174

Metal ion binding

AI721910

1-acylglycerol-3- phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta) (agpat4)

-5.57

0.0020

Acyltransferase activity

NM_200516

zgc:66286 (zgc:66286)

-29.66

0.0015

Calcium ion binding

AF434191

atrial myosin light chain (zgc:66286)

-30.36

0.0009

Undetermined

AF425742

slow muscle myosin heavy chain like (smyhc1l)

-36.63

0.0006

Undetermined

NM_194425

major histocompatibility complex, class I, ZE (mhc1ze)

-67.68

0.0024

Immunity


Schuck et al. BMC Neuroscience 2011 12:88   doi:10.1186/1471-2202-12-88

Open Data