Functional categories of differential gene expression in the zebrafish ear following acoustic trauma. The top fifteen functional categories resulting from IPA Functional Analysis for each of the three pairwise comparisons of differentially expressed zebrafish genes. Values of -log (P-value) are presented such that more significant (i.e., smaller) P-values produce larger bars. P-values were calculated using the right-tailed Fisher Exact Test. Comparisons were made between tissues of control and two-days post-trauma, control and four-days post-trauma, and four- and two-days post-trauma zebrafish. Genes associated with functions such as cancer, cellular growth and proliferation, and inflammation are highly regulated in the zebrafish ear following acoustic trauma.
Schuck et al. BMC Neuroscience 2011 12:88 doi:10.1186/1471-2202-12-88