Immunostaining of α-Syn and p-Tau in WT and Tg mice. Immunohistochemical staining with (A) α-Syn, green, or (B) p-Tau, red, using specific antibodies and DAPI, blue, was conducted as described in Methods. The brain regions pictured top to bottom are: Striatum - Str, Frontal Cortex - FC, Cerebellum - CB, and Brain Stem - BS, in wild type (WT) left panel, and transgenic (Tg) right panel. Inset pictures show 4× magnified region with arrows indicating positive staining of large cellular aggregates. Scale bar: 40 uM, Inset Scale bar: 10 uM.
Kaul et al. BMC Neuroscience 2011 12:79 doi:10.1186/1471-2202-12-79