The monitoring of the secretion of plasma insulin. The data show the concentration of plasma insulin in two groups of ewes housed in constant darkness and given an i.c.v. injection of either (A) metformin or (B) AICAR (open circle) or a synthetic CSF as a control vehicle (closed circle). The arrows depict the time of injection.
Menassol et al. BMC Neuroscience 2011 12:76 doi:10.1186/1471-2202-12-76