Table 2

Architectonic characteristics of orbital PfC






Granular. Layer IV narrower than in 12l. Well stained cells in IIIc. SG layers more prominent than IG.

Intensely stained. Similar to 12l but band in III-IV not discernible.

Intensely stained. Clear bilamination. Many cells in SG and IG bands, with greatest number in III.

Well myelinated. Similar but less intense than 12l.


Granular. Limit between II and IIIa is less evident than in 11m, and layer IV is somewhat narrow. Well stained medium-sized cells in Va.

Moderately stained. Band with moderate neuropil and deeply stained PNs in V reaching layer VI and white matter. In IV small PNs. Very pale PNs in III.

Moderately stained. Clear-cut boundaries with area 12o. Moderate labeling of neuropil and dendritic fragments in SG and IG bands. Small densely stained cell bodies in III and some in IV.

Sparse myelination. OBb and IG layers less stained than 12o


Granular. Thin and sparse layer II. Medium-sized cells with intense pigmentation in IIIc. Densely packed neurons in Va. No clear limits between V and VI.

Lightly stained. Compact and dense band in VI, with moderately stained neuropil and dense PNs.

Discernible bilamination. SG band more stained than in 11l, with cells and processes in III. IG band has moderate staining of neuropil and fragments, but no somas.

Sparse myelination. OBb is faintly stained. Fascicles of vertical fibers in IG layers.


Granular - dysgranular rostrocaudal transition. Layers Vb and VI have moderately stained small-sized neurons.

Moderately stained, increasing caudally. SG band weakly stained, with sparse neuropil and pale PNs. Well stained band in V, reaching VI and white matter.

Moderately stained, decreasing caudally. Bilaminar pattern. IG band with neuropil and fragments. Moderate immunoreactivity in SG band with very few somas and processes in III.

Light to moderate myelination, although stronger than in 13l and 13m. Evident OBb. Fine plexus in SG layers. Moderate staining in IG layers.


Similar to 13i but cells somewhat bigger in Va.

Slightly stained, increasing caudally. No visible superficial band. Narrow band in layer VI.

Moderately stained. IG band similar to 13i. Much lower level of staining in SG layers. No visible bilaminar pattern.

Staining is lighter and more diffuse than in 13i.


Granular - dysgranular rostrocaudal transition. Well developed layer IIIb with sparsely packed small-sized neurons. Cells more stained in IIIc and Va. Vb blends with layer VI.

Poorly stained, increasing caudally.

Similar to 13l.

Similar to 13l but with short vertical fibers in IG layers.


In IIIc and Va cells are larger and more stained than in IIIa-b. No clear limit between Vb and VI.

Poorly stained. No clear-cut limits with areas 11 and 10. Narrow band over layer VI, with pale nets and moderately stained neuropil.

Faintly stained band in IG layers, with neuropil and fragments, and a few somas.

Poorly myelinated. No obvious horizontal bands. Some short and thin vertical fibers in IG layers.


Similar to 14r, but with very faint layers II and IV. Radial striations in IG layers.

Poorly stained. Thin vertical fibers in deep layers.

Similar to 14r, but lighter.

Poorly myelinated.

Cruz-Rizzolo et al. BMC Neuroscience 2011 12:6   doi:10.1186/1471-2202-12-6

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