Table 2

Effect of EGCG treatment on the number of surviving motoneurons and percentage of cell loss in the lesioned side of DMN and HN at 3, 7, 14 and 28 days following PNCI

Days postoperative

Hypoglossal nucleus


Sham

Saline

EGCG

(10 mg/kg)

EGCG

(25 mg/kg)

EGCG

(50 mg/kg)


3

1416 ± 11

1405 ± 8

1408 ± 9

1398 ± 8

1399 ± 9

-

1 ± 0.6%

1 ± 0.6%

1 ± 0.8%

1 ± 0.9%

7

1408 ± 10

1294 ± 18

1304 ± 17

1360 ± 11*

1365 ± 7*

-

9 ± 1.7%

8 ± 1.9%

4 ± 1.2%*

4 ± 1.0%*

14

1411 ± 11

1212 ± 31

1238 ± 20

1318 ± 10*

1331 ± 7*

-

14 ± 2.0%

12 ± 2.0%

7 ± 1.0%*

6 ± 1.0%*

28

1397 ± 8

1165 ± 20

1175 ± 30

1291 ± 5*

1301 ± 5*

-

18 ± 2.0%

17 ± 2.0%

9 ± 1.0%*

8 ± 1.0%*


Days postoperative

Dorsal motor nucleus of vagus nerve


Sham

Saline

EGCG

(10 mg/kg)

EGCG

(25 mg/kg)

EGCG

(50 mg/kg)


3

1284 ± 10

1277 ± 13

1286 ± 8

1293 ± 8

1289 ± 7

-

1 ± 0.5%

0 ± 0.7%

0 ± 0.6%

0 ± 0.7%

7

1292 ± 8

1182 ± 19

1185 ± 16

1227 ± 11*

1235 ± 8*

-

8 ± 1.5%

8 ± 1.6%

4 ± 0.7%*

4 ± 0.7%*

14

1289 ± 11

1055 ± 20

1079 ± 14

1182 ± 13*

1192 ± 7*

-

18 ± 1.3%

16 ± 1.4%

8 ± 0.7%*

7 ± 1.0%*

28

1283 ± 8

952 ± 21

983 ± 17

1021 ± 15*

1091 ± 27*

-

26 ± 1.2%

23 ± 1.4%

20 ± 1.3%*

15 ± 2.3%*


*, p < 0.05 when compared with the saline-treated group

Wei et al. BMC Neuroscience 2011 12:52   doi:10.1186/1471-2202-12-52

Open Data