Table 1

Effect of EGCG treatment on the total number of NADPH-d positive (+) and negative (-) cells in the lesioned side of DMN and HN at 3, 7, 14 and 28 days following PNCI

Days postoperative

Hypoglossal nucleus


Saline

EGCG (10 mg/kg)

EGCG (25 mg/kg)

EGCG (50 mg/kg)


+

-

+

-

+

-

+

-


3

69 ± 4

1336 ± 7

65 ± 3

1343 ± 7

53 ± 4

1344 ± 9

31 ± 4*

1368 ± 7*

7

370 ± 9

924 ± 22

352 ± 11

952 ± 11

238 ± 10*

1121 ± 11*

114 ± 10*

1251 ± 16*

14

235 ± 9

963 ± 34

229 ± 11

1009 ± 29

79 ± 8*

1239 ± 10*

35 ± 7*

1296 ± 12*

28

43 ± 3

1122 ± 19

38 ± 4

1137 ± 31

6 ± 4*

1284 ± 6*

4 ± 3*

1297 ± 5*


Days postoperative

Dorsal motor nucleus of vagus nerve


Saline

EGCG (10 mg/kg)

EGCG (25 mg/kg)

EGCG (50 mg/kg)


+

-

+

-

+

-

+

-


3

368 ± 9

909 ± 6

351 ± 11

934 ± 8

283 ± 12*

1009 ± 18*

222 ± 9*

1067 ± 10*

7

628 ± 21

554 ± 3

590 ± 14

595 ± 9

462 ± 13*

765 ± 17*

433 ± 18*

802 ± 13*

14

616 ± 12

439 ± 20

599 ± 13

480 ± 17

580 ± 11

603 ± 19*

525 ± 17*

667 ± 18*

28

588 ± 16

363 ± 15

586 ± 11

397 ± 14

603 ± 14

418 ± 12*

608 ± 24

482 ± 17*


*, p < 0.05 when compared with the saline-treated group

Wei et al. BMC Neuroscience 2011 12:52   doi:10.1186/1471-2202-12-52

Open Data