Neurochemical analysis of dopaminergic and serotonergic catabolites. Measure of homovanillic acid (HVA), dihydroxyphenylacetic acid (DOPAC) and 5-hydroxyindoleacetic acid (5-HIAA) content in the cortex (A, Cx), hypothalamus (B, Hyp), brainstem and pons (C, BP), caudate-putamen (D, CPu) and midbrain (E, Md) of Mecp2-/y (white bars) and their WT littermates (black bars) at P35 (n = 6 Mecp2-/y, n = 10 WT for Cx, Hyp, BP and CPu - n = 6 Mecp2-/y, n = 9 WT for Md) and P55 (n = 9 Mecp2-/y, n = 8 WT for Cx, Hyp, BP, CPu and Md). Results are expressed as mean +/- S.E.M., (*p < 0.05, **p < 0.01).
Panayotis et al. BMC Neuroscience 2011 12:47 doi:10.1186/1471-2202-12-47