Table 1

The kinetics of mIPSC in normal adult and neuropathic rats

Normal adult

Neuropathic

(Mean ± S.E.)

(Mean ± S.E.)


Rise 10-90% (ms)

Control

1.07 ± 0.1

0.91 ± 0.1

DAMGO

1.10 ± 0.1

0.94 ± 0.0

Decay 90-37% (ms)

τfast

Control

11.74 ± 0.8

8.92 ± 0.4†

DAMGO

13.32 ± 1.3

9.69 ± 0.6†

τslow

Control

39.89 ± 2.2

36.64 ± 2.0

DAMGO

46.50 ± 3.9

36.99 ± 2.5

Weighted mean decay time (ms)

Control

21.03 ± 1.2

17.44 ± 0.9†

DAMGO

23.55 ± 1.8

18.65 ± 1.0†

Half-width (ms)

Control

13.29 ± 0.8

10.29 ± 0.5†

DAMGO

14.66 ± 1.1

11.52 ± 0.6†

Area under currents (pAms)

Control

753.6 ± 42.5

551.4 ± 35.4†

DAMGO

897.0 ± 81.4

567.0 ± 39.1†


Values are mean ± S.E. † P < 0.05 for neuropathic rat compared to that of normal adult rats (Normal adult rat, n = 49 and neuropathic rat, n = 35).

Hahm et al. BMC Neuroscience 2011 12:41   doi:10.1186/1471-2202-12-41

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