Potential Sp1 sites in proximal regions of ΔKal, KalB and KalC promoters. The 1 kilobase of genomic sequence 5' to the Δ, KalB and KalC transcriptional start sites was analyzed using Transcription Factor Search (http://www.cbrc.jp/research/db/TFSEARCH.html webcite); mouse ΔKal (ENSMUST00000114949), rat ΔKal (AF229255.1), human ΔKal (BM920956.1; NM_001024660.2 starts 291 nt further 3'), mouse KalB (U88156.1) and mouse KalC (AF230644.1; NM_177357). The Sp1 consensus site definition is from . Only one human cDNA corresponding to the mouse and rat ΔKal transcripts was identified; the 5' extent of the human transcript may be longer than depicted here, making the distance from the Sp1 site to the start of transcription shorter.
Mains et al. BMC Neuroscience 2011 12:20 doi:10.1186/1471-2202-12-20