Table 2

Cyto-chemokine production at baseline and after 1 month of therapy in SC patients

Variable

Pre treatment

Post treatment

Wilcoxon U test p-value


MCP-1

Basal

11360.9 ± 759.2

10840.5 ± 661.5

0.012

LPS

19579.6 ± 803.9

19321.5 ± 1373.5

0.005

RANTES

Basal

1071.5 ± 174.9

1161.2 ± 134.4

0.005

LPS

11755.4 ± 451.3

12125.0 ± 502.8

0.005

IL-18

Basal

62.9 ± 4.9

68.3 ± 5.7

0.005

LPS

298.0 ± 15.1

317.7 ± 14.2

0.005


Mean ± standard deviation of RANTES, MCP-1 and IL-18 levels (pg/ml) released by non-stimulated and LPS-stimulated PBMC from 10 SC patients at time of enrolment and after 1 months of treatment with atypical antipsychotic drugs.

Reale et al. BMC Neuroscience 2011 12:13   doi:10.1186/1471-2202-12-13

Open Data