Comparison of chemokine production between SC patients and healthy controls. MCP-1, MIP-1α, IL-8 and RANTES release by non-stimulated and LPS-stimulated PBMC (pg/ml/106 cells) from 40 healthy controls (HC) and 51 schizophrenic (SC) patients. Supernatants were collected, stored at -80°C until analysis than measured for MCP-1, MIP-1α, IL-8 and IL-18 concentration using a commercial enzyme-linked immunosorbent assay (ELISA). All samples for a given assay were analyzed in duplicate at the same time. The ELISA values (in duplicates for each sample) have an error range lower than 10%. The variation coefficient of both inter-assay and intra-assay was <5%. Each data point represents the release of MCP-1, MIP-1α, IL-8 and RANTES from each patient. Horizontal bars indicate group mean values.
Reale et al. BMC Neuroscience 2011 12:13 doi:10.1186/1471-2202-12-13