Table 2

Correlation data for candidate genes.

Column1

Gene

Slope

95% Confidence Intervals

Goodness of Fit, R square

P value

n


Ad libitum

Pfn2

0.57

-0.1531 to 1.286

0.29

0.107

10


Chow fed

Ntrk2

0.55

0.1165 to 0.9898

0.52

0.019

10


Mice

Bdnf

-0.47

-0.7881 to -0.1488

0.63

0.011

10


Prkacb

-0.06

-0.3902 to 0.2681

0.02

0.680

10


Vamp2

0.29

-2.319 to 2.905

0.01

0.793

8


Stat3

0.50

-1.635 to 2.626

0.05

0.590

8


Nln

0.63

-1.469 to 2.737

0.08

0.489

8


Btbd12

2.38

-3.681 to 8.433

0.13

0.374

8


Zbtb20

2.29

-1.129 to 5.710

0.31

0.152

8


Atf7ip

-

-

-

-

-


Food deprived

pfn2

1.19

0.2082 to 2.171

0.66

0.026

8


mice

Ntrk2

0.09

-0.54 to 0.73

0.03

0.724

8


Bdnf

0.06

-52 to 0.64

0.02

0.792

8


Prkacb

-0.04

-1.198 to 1.113

0.00

0.932

8


Vamp2

0.71

-0.5620 to 1.983

0.24

0.221

8


Stat3

0.54

0.01046 to 1.078

0.51

0.047

8


Nln

0.71

-0.4190 to 1.832

0.28

0.175

8


Btbd12

1.69

0.1775 to 3.198

0.55

0.034

8


Zbtb20

0.65

-0.3582 to 1.664

0.29

0.165

8


Atf7ip

-

-

-

-

-


The expression of genes in bold text are significantly correlated to expression of Fto (p < 0.05). Genes in cursive text were run on chow fed mice in the 16 hour food restriction paradigm. Hypothalamic expression of Ntrk2 and Bdnf correlate to Fto-expression positively and negatively, respectively, in ad libitum chow fed mice. Pfn2, Stat3 and Btbd12 were positively correlated to expression of Fto in hypothalami of 16 hour food restricted mice.

Rask-Andersen et al. BMC Neuroscience 2011 12:117   doi:10.1186/1471-2202-12-117

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