Table 1

Time course of SHS on rat cerebral artery contractions induced by K+, S6c and ET-1.

Exposure time (week)

Group

n

K+ (mN)

S6c

(Emax % of K+)

ET-1

(Emax % of K+)


2

Fresh air

4

5.6 ± 0.58

8.5 ± 0.9

127 ± 14

SHS

3

5.8 ± 0.63

8.3 ± 1.0

132 ± 15

4

Fresh air

4

5.4 ± 0.52

8.9 ± 1.1

131 ± 17

SHS

4

6.2 ± 0.69

9.1 ± 1.3

136 ± 19


The cerebral arteries were from groups of fresh air and SHS for 2 and 4 weeks. K+-induced responses were expressed as absolute values of contraction (mN). S6c and ET-1-induced responses were expressed as percentage of K+-induced contraction. Emax, maximal contraction; SHS, secondhand smoke exposure.

Cao et al. BMC Neuroscience 2011 12:109   doi:10.1186/1471-2202-12-109

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