Sections from the basilar artery showing pERK immunoreactivity in the smooth muscle cell layer. a) pERK1/2; sham, b) pERK1/2; SAH, c) pERK; SAH treated with SB386023-b after 6 h, d) pERK; SAH treated with SB386023-b after 12 h, There are increased expressions of the pERK1/2 protein levels in the SAH compared to the sham operated rats. Treatment with SB386023-b after 6 h prevented the increased protein expression in the smooth muscle cells. Data were obtained with confocal microscopy.
Ansar et al. BMC Neuroscience 2011 12:107 doi:10.1186/1471-2202-12-107