F2 USVs were diversified into B6-like, 129-like, and mixed phenotypes. (a) USV patterns of F2 mice. Representative sonograms of the four types of F2 mice are shown. Chevron repeat (red) and short repeats (blue) are highlighted (box). (b) Proportions of short (x-axis) and chevron (y-axis) for each mouse are shown. One dot is one mouse. Short and chevron compositions for B6 (blue) and F1 (green) overlapped, whereas 129 USVs (red) were discrete. F2 (black) mice were B6-like and 129-like, containing both chevron and short rich repeats, while others lacked chevrons and short syllables. (c) The ratio of F2 mice with syllable repeats greater than four. Chevron-rich USVs were recessive, whereas short-rich USVs were dominant.
Choi et al. BMC Neuroscience 2011 12:104 doi:10.1186/1471-2202-12-104