Table 1

Genomic locations of Kv3 family orthologs in zebrafish genome (Zv8)

Chromosome

Identity1

Strand

N-term. Exon2

S1-S6 Exon2

Prox. C-term. Exon2

Distal C Exon2

Alt. C Exon2


7

kcnc1a

+

33,357,526

33,399,062

33,413,557

33,416,890

33,417,909

25

kcnc1b

-

4,398,437

4,372,686

4,369,562

4,367,934

43

kcnc2

-

2,653,160

2,619,906

2,617,395

2,614,222

3

kcnc3a

+

29,217,143

29,277,151

29,286,001

29,288,301

29,305,269

24

kcnc3b

-

35,119,4374

35,441,453

35,436,978

35,394,285(+)5

8

kcnc4

-

25,733,068

25,708,221

25,706,162

25,696,460


1 Identities were assigned on the basis of the phylogenetic and syntenic analyses shown in Figs. 1-3.

2 The identified exons encode the N-terminus, the S1-S6 membrane domain, the proximal portion of the C-terminus, and one or more putative sequences for the distal C-terminus, which may be alternatively spliced. The numbers correspond to the chromosomal positions of each exon.

3 According to Zv8, there is an additional exon encoding a Kv3 N-terminus on chromosome 4 (minus strand) at position 2,762,001. Because previous genome releases contained stray Kv3 exons that disappeared in subsequent releases, this exon is likely to reflect an assembly error (data not shown).

4 In Zv8, the N-terminal exon of kcnc3b (italics) is out of order compared to the other exons.

5 In Zv8, the distal C-terminal exon of kcnc3b has been mapped to the plus strand, in contrast to the other exons.

Mock et al. BMC Neuroscience 2010 11:99   doi:10.1186/1471-2202-11-99

Open Data