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Gene expression changes in the medial prefrontal cortex and nucleus accumbens following abstinence from cocaine self-administration

Willard M Freeman12*, Melinda E Lull1, Kruti M Patel2, Robert M Brucklacher2, Drake Morgan3, David CS Roberts4 and Kent E Vrana1

  • * Corresponding author: Willard M Freeman

  • † Equal contributors

Author Affiliations

1 Department of Pharmacology, Penn State College of Medicine, Hershey, PA, 17033, USA

2 Functional Genomics Facility, Penn State College of Medicine. Hershey, PA, 17033, USA

3 Department of Psychiatry, University of Florida, Gainesville, FL, 32611, USA

4 Department of Physiology & Pharmacology, Wake Forest University School of Medicine, Winston-Salem, NC, 27157, USA

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BMC Neuroscience 2010, 11:29  doi:10.1186/1471-2202-11-29

Published: 26 February 2010

Additional files

Additional file 1:

Microarray expression data. A full listing of differentially expressed genes identified by microarray analysis.

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Additional file 2:

Gene expression assay numbers. Gene symbols, full names and gene expression assay numbers.

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Additional file 3:

Dissection schematics. Dissection diagrams. Schematics of the mPFC and NAc dissections are provided using modifications of figures from Paxinos and Watson. Numbered red lines are specific dissection cuts using visible landmarks as described in the methods. The shaded area represents the tissue collected for molecular analysis.

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