Table 3

Group-level brain activations

MNI Coordinates


Brain region

X

Y

Z

Maximum

Z-value

Cluster size

(mm3)

Cluster P-

value

Acute pain

network regions1


Secondary somatosensory cortex (left)

-60

-12

3

10.3

10431

3.20E-42

Primary somatosensory cortex (left)*

-54

-11

37

8.87

-

-

Primary auditory cortex (right)

54

0

-11

9.22

6709

5.31E-32

Secondary somatosensory cortex (right)*

51

-31

18

8.1

-

-

Cerebellum posterior lobe (left)

-44

-79

-30

8.12

6346

6.50E-31

Cerebellum posterior lobe (right)

23

-72

-23

9.63

5745

4.57E-29

Premotor cortex (right)

48

1

44

8.29

2027

1.41E-15

Thalamus (right)

4

-19

5

6.93

1221

1.01E-11

Thalamus (left)*

-6

-23

4

6.82

-

-

Prefrontal cortex (left)

-6

40

-27

9.87

930

3.96E-10

Visual cortex V3 (left)

-30

-98

-15

7.22

560

5.96E-08

Middle temporal gyrus (right)

61

-34

-2

5.69

366

2.03E-06

Premotor cortex (left)

-15

13

61

7.18

296

7.39E-06

Insular cortex (right)

38

11

1

6.97

196

5.84E-05

Anterior caudate nuclei (left)

-21

25

0

6.49

159

0.00014

Anterior caudate nuclei (right)

12

26

-2

6.01

119

0.00037


Group results from FSL analysis. Cluster-threshold of Z ≥ 5 and p = 0.001. Decreasing cluster size order. MNI, Montreal Neurological Institute

1From Apkarian et al, 2005

*Local maxima within the above cluster

Moana-Filho et al. BMC Neuroscience 2010 11:142   doi:10.1186/1471-2202-11-142

Open Data