Figure 5.

Immunohistochemistry using an amyloid-pre-absorbed anti-Chlamydia pneumoniae antibody. Panels A-D illustrate anti-C. pneumoniae immunoreactivity (red) in frontal AD tissue. The antibody for detection of C. pneumoniae is a mouse monoclonal C. pneumoniae antibody (Table 1, #3). Panel A illustrates the extent of anti-C. pneumoniae immunoreactivity with the non-pre-absorbed antibody. Panel B shows the extent of immunolabeling on the tissue when labeled with the 1-40 pre-absorbed antibody (pre-absorbed against >10 molar excess Sigma amyloid Aβ1-40 peptide). Panels C and D (higher power of panel C) show the extent of immunolabeling on the tissue when labeled with the 1-42 pre-absorbed antibody (pre-absorbed against >10 molar excess Sigma amyloid Aβ1-42 peptide). Size bar for panels A-C = 50 μm and panel D = 20 μm.

Hammond et al. BMC Neuroscience 2010 11:121   doi:10.1186/1471-2202-11-121
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