Impaired survival of newly generated cells in the two neurogenic regions of the olfactory bulb in HD mice compared to controls. Significant reduction of BrdU-labeled newly generated cells in the GCL and the GLOM 4 weeks after BrdU administration in R6/2 mice compared to controls (C, G). Representative images of immunostainings for BrdU in the GCL (A, B) and the GLOM (E, F) of both groups. Schematic representation of the OB areas analyzed (D). Error bars represent SD, * indicates p < 0.05. Scale bars represent 50 μm.
Kohl et al. BMC Neuroscience 2010 11:114 doi:10.1186/1471-2202-11-114