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Resolution: standard / high Figure 4.
Comparison of the dyslexic subjects' brain classifications for data smoothed with
a 4, 8 or 12 mm FWHM isotropic Gaussian kernel (from left to right). For the three sizes, significant clusters of differences were obtained in the right
cerebellar declive (corrected p values ~0; cluster size under H0 for voxels with 100%
of difference = 0.36 +/- .05 at 4 mm smoothing, 0.531 +/- 0.07 at 8 mm smoothing,
1.33 +/- .09 at 12 mm smoothing). By contrast, only one cluster was observed in the
right lentiform nucleus with a 8 mm smoothing kernel vs. 1 voxel only with a 4 mm
or 12 mm smoothing kernel. As illustrated, the coordinates of the centres of mass
(or single voxel) differed with the smoothing kernel. However, by lowering the threshold
of the PMD from 100% to 95%, there is a clear overlap between the three PMD (right
hand side), confirming the robustness of the results.
Pernet et al. BMC Neuroscience 2009 10:67 doi:10.1186/1471-2202-10-67 |