Exercise effect on learning of the cued version of the Morris water maze (MWM) in the chronic MPD. (A) One day and (B) 10 weeks after MPTP/probenecid treatment, the chronic MPD group of mice showed significant impairment in learning the cued version of the MWM when compared with the controls (A, *P = 0.01 and B, *P = 0.012, respectively). (B) Continuous exercise for 10 weeks after MPTP/probenecid treatment did not alter the learning deficit for the cued version of the MWM in the chronic MPD (**P = 0.557, when compared to the sedentary chronic MPD).
Pothakos et al. BMC Neuroscience 2009 10:6 doi:10.1186/1471-2202-10-6