Effect of exercise on the step length in the chronic MPD. The mean step length in the sedentary chronic MPD mice 12 weeks after MPTP/probenecid treatment was significantly shorter than the probenecid-treated controls (*P = 0.0001). Continuous exercise for 12 weeks after MPTP/probenecid treatment in the chronic MPD completely reversed the step length deficit as detected in the sedentary chronic MPD group (**P = 0.0001). The mean step length in the control group and exercised chronic MPD group were not statistically different.
Pothakos et al. BMC Neuroscience 2009 10:6 doi:10.1186/1471-2202-10-6