Both running and lesioning affected survival of newborn cells. (A) Running increased numbers of BrdU-labelled newborn cells surviving at 4 weeks in both the non-lesioned (* p < 0.05) and lesioned groups (§p < 0.05). (B) The survival of BrdU-labelled cells at 4 weeks was expressed as a percentage of the number of cells counted at 24 hrs after BrdU injection. The percentage of BrdU-labelled cells that survived for 4 weeks was significantly reduced in the cholinergic lesioned runners (** p < 0.001). Data are mean ± sem.
Ho et al. BMC Neuroscience 2009 10:57 doi:10.1186/1471-2202-10-57