Table 1

Summary of in vivo RGC counts. Systemic and topical application of G-CSF or vehicle.

Experimental Group

Animal

RGCs per mm2

Mean

S.E.M.


axotomy + vehicle injection s.c.

1

360


2

348


3

594


4

379

420.6

58.4


axotomy + vehicle injection i.o.

1

443


2

390


3

378


4

435


5

365

402.2

15.5


axotomy + G-CSF 20 μg/kg BW s.c. daily

1

669


2

442


3

554


4

649

578.9

52.0


axotomy + G-CSF 40 μg/kg BW s.c. daily

1

729


2

637


3

778


4

704


5

773

742.3

25.8


axotomy + G-CSF 40 μg/kg BW s.c. daily (start 1 d before surgery)

1

641


2

876


3

696


4

872

771.3

60.3


axotomy + G-CSF 500 ng i.o. on days 0, 4, 7 and 10 after axotomy

1

638


2

613


3

773


4

703

681.8

35.8


Cell numbers are given as mean ± S.E.M. s.c.: subcutaneous; i.o.: intraocular; BW: bodyweight.

Frank et al. BMC Neuroscience 2009 10:49   doi:10.1186/1471-2202-10-49

Open Data