Additional file 2.
Confocal microscopy shows co-localization of MMP-7 with tomato lectin and Gr-1. (a) Confocal image of tomato lectin-stained cells (red) in a vascular cuff in the brain of a wt mouse during EAE, 15 days after vaccination with a clinical score of 1. (b) Confocal image of the same section in a showing MMP-7 immunostaining (green). (c) Merged image of boxes a and b shows co-localization of MMP-7 and tomato lectin in a perivascular accumulation of immune cells during EAE. (d) Confocal image of Gr-1 immunopositive cells (red) in the brain of a WT mouse during EAE. (e) Confocal image of the same section in d showing MMP-7 immunopositive cells (green). (f) Merged image of d and e shows co-localization of MMP-7 and Gr-1.
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Buhler et al. BMC Neuroscience 2009 10:17 doi:10.1186/1471-2202-10-17