Open Access Highly Accessed Research article

Imaging short- and long-term training success in chronic aphasia

Ricarda Menke12, Marcus Meinzer13*, Harald Kugel4, Michael Deppe1, Annette Baumgärtner5, Hagen Schiffbauer4, Marion Thomas1, Kira Kramer1, Hubertus Lohmann1, Agnes Flöel1, Stefan Knecht16 and Caterina Breitenstein1

  • * Corresponding author: Marcus Meinzer mmeinzer@ufl.edu

  • † Equal contributors

Author Affiliations

1 Department of Neurology, University of Münster, Münster, Germany

2 Department of Clinical Neurology, Oxford University, Oxford, UK

3 Department of Clinical & Health Psychology, University of Florida, Gainesville, USA

4 Department of Clinical Radiology, University of Münster, Münster, Germany

5 Department of Health Sciences, Hochschule Fresenius, University of Applied Sciences, Hamburg, Germany

6 Neurocenter, Schön Klinik, Hamburg, Germany

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BMC Neuroscience 2009, 10:118  doi:10.1186/1471-2202-10-118

Published: 22 September 2009

Additional files

Additional file 1:

Patient Information. Demographic and clinical information and language test results for the eight aphasia patients

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Additional file 2:

Supporting information. Provides additional supportive information regarding patient characteristics, neuropsychological testing and functional imaging analyses and results

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Additional file 3:

Brain activity changes immediately after training and at the follow-up assessment. Brain activity changes in the patients and healthy controls: Brain areas showing a) positive and b) negative correlations between short-term training success and 'post1-pre' training activity changes for trained object names (masked with the respective results for untrained object names). Brain areas showing c) positive and d) negative correlations between long-term training success and 'post2-pre' training activity changes for trained object names (masked with the respective results for untrained object names). The corresponding results for the control group (Session1 versus Sesssion2) are displayed in italic font

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