Table 1

Differential gene expression results in EMBs from DCM and DCMi patients related to HPRT-CCM and CDKN1B using T-PreAmp

Gene

DCM

DCMi

p value


CD3d

0.014163 ± 0.008761

0.045395 ± 0.015252

<0.0001

CD3z

0.043139 ± 0.010119

0.060631 ± 0.007718

0.0023

TRBC

0.015027 ± 0.010150

0.027622 ± 0.010532

0.0098

TRBV2

0.001487 ± 0.001300

0.004503 ± 0.002881

0.0053

TRBV4

0.001501 ± 0.001432

0.005441 ± 0.003850

0.0047

TRBV6

0.002926 ± 0.002154

0.005478 ± 0.002562

0.0307

TRBV10

0.000186 ± 0.000127

0.000905 ± 0.000967

0.0245

TRBV20

0.003935 ± 0.003140

0.019818 ± 0.018318

0.0105

TRBV23

0.000408 ± 0.000269

0.006402 ± 0.008324

0.0270

TRBV24

0.000282 ± 0.000265

0.004754 ± 0.006232

0.0075

TRBV29

0.001302 ± 0.001168

0.002815 ± 0.00138

0.0192

IL6

0.002020 ± 0.001246

0.004133 ± 0.002452

0.0094

TNFa

0.028511 ± 0.014230

0.052024 ± 0.017001

0.0049

CXCL14

0.151853 ± 0.145437

0.054158 ± 0.052000

0.0299

CX3CL1

0.96874 ± 0.431717

1.39651 ± 0.790158

0.0245

APN

0.390377 ± 0.555952

0.035850 ± 0.058782

0.0092

NFATC3

1.29493 ± 0.479396

2.56855 ± 0.776956

0.0052

CYR61

0.85785 ± 0.47640

2.94840 ± 2.33843

<.0001

TF

3.59608 ± 1.01046

2.14158 ± 0.53169

0.0109

T-bet

0.014431 ± 0.005826

0.022267 ± 0.008127

0.0355

Granzyme A

0.014704 ± 0.006914

0.035028 ± 0.011726

0.0004

Granzyme B

0.062487 ± 0.022406

0.105532 ± 0.026082

0.0027

Granulysin

0.206285 ± 0.186560

0.532339 ± 0.327002

0.0183

Eomesodermin

0.014428 ± 0.007246

0.036024 ± 0.007900

0.0011

av5b1

1.04571 ± 0.283760

1.71316 ± 0.844310

0.0033

GDF15

0.020984 ± 0.013187

0.041715 ± 0.028283

0.0127

CD62E

0.002714 ± 0.001093

0.012877 ± 0.008890

0.0119


Significantly different gene expression (E; normalized to the housekeeping genes HPRT-CCM or CDKN1B) T-PreAmp real-time RT-PCR results in EMBs from DCM patients compared with EMBs from patients with immunohistologically confirmed DCMi (>7 CD3+ infiltrates/mm2). The values are given as means ± SD, followed by the respective p values in significantly different comparisons.

Noutsias et al. BMC Molecular Biology 2008 9:3   doi:10.1186/1471-2199-9-3

Open Data