Table 3

Housekeeping gene expression following vehicle/hormone/toxicant treatment from 24–96 hpf, as measured by QPCR

Ct values +/- S.E.M.

GENE
CONTROL
ETOH
DMSO
0.1 μM E2
1 μM T
10 μM ICI
10 nM BNF
1 nM TCDD

bactin1
15.1 ± 0.07
14.9 ± 0.01
15.2 ± 0.12
15.0 ± 0.03
14.7 ± 0.08
15.1 ± 0.05
15.5 ± 0.19
15.1 ± 0.02
tuba1
19.9 ± 0.11
19.5 ± 0.08
19.6 ± 0.08
20.0 ± 0.13
19.3 ± 0.08
19.8 ± 0.04
19.7 ± 0.05
19.5 ± 0.08
gapdh
16.8 ± 0.12
16.1 ± 0.20*
16.0 ± 0.10*
15.9 ± 0.02
15.9 ± 0.07
15.8 ± 0.03
15.9 ± 0.11
16.1 ± 0.06
g6pd
21.4 ± 0.11
20.7 ± 0.04*
20.8 ± 0.03
21.5 ± 0.06
20.8 ± 0.01
20.8 ± 0.03
21.4 ± 0.16
21.1 ± 0.07
tbp
20.4 ± 0.53
21.6 ± 0.14
20.6 ± 0.31
21.4 ± 0.05
21.9 ± 0.15
21.9 ± 0.06
22.1 ± 0.13
22.3 ± 0.25
b2m
23.8 ± 0.16
23.0 ± 0.13
22.9 ± 0.23
23.6 ± 0.10
24.3 ± 0.43
24.0 ± 0.44
24.5 ± 0.30
24.2 ± 0.16
elfa
14.6 ± 0.12
14.2 ± 0.01*
14.2 ± 0.01*
14.2 ± 0.05
14.4 ± 0.12
14.3 ± 0.05
14.4 ± 0.07
14.3 ± 0.03
18s
16.2 ± 0.02
16.3 ± 0.08
16.8 ± 0.18*
16.3 ± 0.03
16.3 ± 0.03
16.3 ± 0.15
16.3 ± 0.02
16.9 ± 0.09

Values represent Ct values (mean +/- SEM) from 3 biological replicates (50 embryos/larvae per pool, 3 pools per treatment group). For details, see Methods and Results. Asterisks (*) indicate significant difference between vehicle [dimethyl sulfoxide (DMSO), ethanol (EtOH)] and control (control = untreated; p < .05). Boldface indicates significant difference between treatment [17β-estradiol (E2), testosterone (T), ICI 182,780 (ICI), β-napthaflavone (BNF), tetrachlodibenzo-p-dioxin (TCDD)] and DMSO (p < .05).

McCurley and Callard BMC Molecular Biology 2008 9:102   doi:10.1186/1471-2199-9-102