Additional file 3: Figure S2.

Mutational analysis of Pax-like cis-elements in the RPP with 5′ upstream sequences: Effect on Otx5-LNrl activation. Cells were transiently transfected with a plasmid containing a wild type promoter (XOP(−5361/+41)) or a mutation in cis-element (s) (m1-m10, see Figure4A) in the absence (No TF) or presence of Otx5-LNrl. Activities in cell lysates are presented as mean ± S.E.M (n = 6-8). Promoter basal activity (RLU) is shown in parentheses.

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Reks et al. BMC Molecular Biology 2014 15:4   doi:10.1186/1471-2199-15-4