VprBP structural motifs and interacting proteins. The 1507 amino acid human VprBP isoform encoded by transcript variant ENST00000563997 in the Ensembl database (release 71)  is shown with the domain features for this isoform as described in the database or in the text. VprBP-interacting proteins are identified below the diagram; those for which the binding site has been mapped are shown below the region mediating the association. Proteins targeted for VprBP-dependent ubiquitination are boxed. The region removed after Cre-mediated deletion of a conditional allele , and the location of a DNA-PK-dependent phosphorylation site  are also indicated.
Nakagawa et al. BMC Molecular Biology 2013 14:22 doi:10.1186/1471-2199-14-22