Figure 4.

Differential effect of TSA on ABCB1 alternative promoters. Group A cell lines (Hs-766 T, IMIM-PC-1, IMIM-PC-2, RWP1, PANC-1, MCF-7, K-562, HT-29, HT-29/M6, SW620 and BxPC-3) expressing the short 5UTR MDR1 mRNA and group B cell lines (HTC-15, K5-62/Adr and MCF-7/Adr) expressing the long 5UTR MDR1 mRNAs were treated for 24 hours with 1 μM TSA. As internal control GAPDH mRNA was also determined. Results are shown as the mean ± SD of at least three independent experiments with three replicates in each experiment.

Balaguer et al. BMC Molecular Biology 2012 13:25   doi:10.1186/1471-2199-13-25
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