Table 1

Yhr087wp interacting proteins according to the TAP experiments carried out in this work
Protein Function(1)
Atp7p Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase
Osh7p Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability
Cmk1p Calmodulin-dependent protein kinase; may play a role in stress response
Cmk2p Calmodulin-dependent protein kinase; may play a role in stress response
Sti1p Hsp90 cochaperone, interacts with the Ssa group of the cytosolic Hsp70 chaperones and activates Ssa1p ATPase activity
Tfg1p TFIIF (Transcription Factor II) largest subunit; involved in both transcription initiation and elongation of RNA polymerase II;
Cdc33p Cytoplasmic mRNA cap binding protein and translation initiation factor eIF4E; the eIF4E-cap complex is responsible for mediating cap-dependent mRNA translation via interactions with translation initiation factor eIF4G (Tif4631p or Tif4632p)
Scp160p Essential RNA-binding G protein effector of mating response pathway, mainly associated with nuclear envelope and ER, interacts in mRNA-dependent manner with translating ribosomes via multiple KH domains, similar to vertebrate vigilins
Tif32p eIF3a subunit of the core complex of translation initiation factor 3 (eIF3), essential for translation
Tif4631p Translation initiation factor eIF4G, subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); interacts with Pab1p and with eIF4A (Tif1p); also has a role in biogenesis of the large ribosomal subunit

(1) The description according to Saccharomyces Genome Database (SGD) is shown.

Gomar-Alba et al.

Gomar-Alba et al. BMC Molecular Biology 2012 13:19   doi:10.1186/1471-2199-13-19

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