Table 1 |
|
| Yhr087wp interacting proteins according to the TAP experiments carried out in this work | |
| Protein | Function(1) |
| Atp7p | Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase |
| Osh7p | Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability |
| Cmk1p | Calmodulin-dependent protein kinase; may play a role in stress response |
| Cmk2p | Calmodulin-dependent protein kinase; may play a role in stress response |
| Sti1p | Hsp90 cochaperone, interacts with the Ssa group of the cytosolic Hsp70 chaperones and activates Ssa1p ATPase activity |
| Tfg1p | TFIIF (Transcription Factor II) largest subunit; involved in both transcription initiation and elongation of RNA polymerase II; |
| Cdc33p | Cytoplasmic mRNA cap binding protein and translation initiation factor eIF4E; the eIF4E-cap complex is responsible for mediating cap-dependent mRNA translation via interactions with translation initiation factor eIF4G (Tif4631p or Tif4632p) |
| Scp160p | Essential RNA-binding G protein effector of mating response pathway, mainly associated with nuclear envelope and ER, interacts in mRNA-dependent manner with translating ribosomes via multiple KH domains, similar to vertebrate vigilins |
| Tif32p | eIF3a subunit of the core complex of translation initiation factor 3 (eIF3), essential for translation |
| Tif4631p | Translation initiation factor eIF4G, subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); interacts with Pab1p and with eIF4A (Tif1p); also has a role in biogenesis of the large ribosomal subunit |
(1) The description according to Saccharomyces Genome Database (SGD) is shown.
Gomar-Alba et al. BMC Molecular Biology 2012 13:19 doi:10.1186/1471-2199-13-19