Table 2

Bioinformatics analysis of TspDTI domains and functional motifs

Residues

domain

HHPRED

PCONS score

predicted function


1 ~ 160

PD-(D/E)XK

1m0d (Endo I) 21

1avq (λ exonuclease) 0.18

Mg2+-binding/DNA cleavage


~160-360

helical linker

no match

no match

interactions between domains


~360-790

RFM

2ar0 (M.EcoKI) 4.6e-36

2adm (M.TaqI) 1.9

SAM-binding/methylation


~790-

TRD

1ih2 (M.TaqI) 1.9e-13

1yf2 (S.MjaORF132P) 0.374

DNA-binding


Zylicz-Stachula et al. BMC Molecular Biology 2012 13:13   doi:10.1186/1471-2199-13-13

Open Data