Diagram of the microplate-based Matrix ChIP-MeDIP method. Batches of polypropylene plates are coated overnight with protein A (room temperature) and are then stored sealed up to 2 weeks (4°C) and used when needed. Starting with protein A-coated plates the ChIP-MeDIP assay takes 4-5 hours to generate PCR-ready DNA. Detailed protocol is described in "Method" section. The red and yellow lines exemplify rows of wells with ChIP and MeDIP antibodies, respectively.
Yu et al. BMC Molecular Biology 2011 12:49 doi:10.1186/1471-2199-12-49