Table 1

Alternative uPAR splicing identified in the RACE analyses

Variant

5'Donor site

3'Acceptor site

Implication


E3 deletion

GCGCTTGTGGGAAG

GCCGGGCTGTCAC

In frame deletion, removal of 48 residues

E4+5 deletion

CCAGGGCAACTCTG

TCCTGGAGCTTGA

In frame deletion, removal of 100 residues, valine insertion

E5 deletion

AGGTGAAGAAG

TCCTGGAGCTTGA

In frame deletion, removal of 46 residues, valine insertion

E6 deletion

(with E7)

CAACGAGGGCCCAA

AACCGAAAAACC

In frame deletion, removal of 50 residues, lysine insertion

E6 deletion

(with E7b)

CAACGAGGGCCCAA

AACGCTCACTCTGG

In frame deletion, removal of 50 residues, lysine insertion

E5+6 deletion

(with E7)

AGGTGAAGAAG

AACCGAAAAACC

In frame deletion, removal of 94 residues

E3+4+5 deletion

GCGCTTGTGGGAAG

TCCTGGAGCTTGA

In frame deletion, removal of 148 residues, valine insertion


uPAR variants detected at >5% frequency in RACE analysis are included.

Stewart and Sayers BMC Molecular Biology 2009 10:75   doi:10.1186/1471-2199-10-75

Open Data