Case study. A clustering tree built using the the complete linkage hierarchical clustering algorithm and the F84 distances for 114 coding sequences of DENV-3 virus envelope proteins of isolates collected in Thailand and having collection year on record. Sequences obtained prior to 1992 were selected using the tree viewing option menu and highlighted in red. Most of pre-1992 DEV-3 sequences in Thailand fall in a distinct cluster.
Resch et al. BMC Microbiology 2009 9:65 doi:10.1186/1471-2180-9-65