Table 2 |
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Top paths in the MAP-RES network |
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Path |
Score |
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SOS |
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Rv0242c (FabG4) -(276)→Rv2245 (KasA) -(596)→Rv2737c (RecA) |
0.0102 |
|
Rv0242c -(276)→Rv2245 -(596)→Rv2737c -(44)→Rv2720 (LexA) |
0.0727 |
|
Rv0904c (AccD3) -(241)→Rv1547 (DnaE1) |
0.1000 |
|
Rv0824c (DesA1) -(162)→Rv0823c -(247)→Rv2737c |
0.1344 |
|
Rv0242c -(276)→Rv2245 -(596)→Rv2737c -(96)→Rv2593c (RuvA) |
0.1352 |
|
Rv2246 (KasB) -(400)→Rv1131 (GltA1) -(526)→Rv1629 (PolA) |
0.1389 |
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CYTOCHROMES |
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|
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Rv2243 (FabD) -(200)→Rv3546 (FadA5) -(395)→Rv3545c (Cyp125) |
0.0174 |
|
Rv0242c -(436)→Rv2243 -(200)→Rv3546 -(395)→Rv3545c |
0.0203 |
|
Rv1350 (FabG2) -(205)→Rv2243 -(200)→Rv3546 -(395)→Rv3545c |
0.0230 |
|
Rv1483 (FabG1) -(121)→Rv2243 -(200)→Rv3546 -(395)→Rv3545c |
0.0352 |
|
Rv2243 -(257)→Rv0769 -(558)→Rv0766c (Cyp123) |
0.0643 |
|
Rv0242c -(436)→Rv2243 -(559)→Rv2782c (PepR) -(513)→Rv1622c (CydB) |
0.0655 |
|
Rv0242c -(436)→Rv2243 -(257)→Rv0769 -(558)→Rv0766c (Cyp123) |
0.0673 |
|
Rv0242c -(436)→Rv2243 -(559)→Rv2782c -(578)→Rv2193 (CtaE) |
0.0738 |
|
Rv0643c (MmaA3) -(350)→Rv0892 -(350)→Rv0568 (Cyp135B1) |
0.0956 |
|
Rv0643c -(350)→Rv0892 -(350)→Rv3059 (Cyp136) |
0.0956 |
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ANTIBIOTIC EFFLUX PUMPS |
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|
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Rv2245 -(565)→Rv0340 -(447)→Rv0342 (IniA) |
0.0526 |
|
Rv0242c -(276)→Rv2245 -(565)→Rv0340 -(447)→Rv0342 |
0.0580 |
|
Rv2243 -(356)→Rv2238c (AhpE) -(569)→Rv2687c |
0.0901 |
|
Rv2243 -(2)→Rv2245 -(565)→Rv0340 -(447)→Rv0342 |
0.1151 |
|
Rv0642c (MmaA4) -(350)→Rv3248c (sahH) -(486)→Rv3240c -(323)→Rv3239c |
0.1365 |
|
Rv0642c -(350)→Rv3248c -(350)→Rv1988 |
0.1385 |
|
Rv1350 -(90)→Rv2245 -(596)→Rv2737c -(429)→Rv2882c (Frr) -(584)→Rv0783c (EmrB) |
0.3169 |
|
Rv2245 -(369)→Rv1908c (KatG) -(350)→Rv1988 |
0.3833 |
|
Rv0242c -(276)→Rv2245 -(369)→Rv1908c -(350)→Rv1988 |
0.3888 |
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HORIZONTAL GENE TRANSFER |
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Rv0644c (MmaA2) -(350)→Rv3248c -(486)→Rv3240c (SecA1) |
0.0812 |
|
Rv2243 -(202)→Rv2925c (Rnc) -(378)→Rv3659c |
0.0913 |
|
Rv2243 -(202)→Rv2925c -(378)→Rv3659c -(63)→Rv3660c |
0.1538 |
|
Rv2245 -(596)→Rv2737c -(514)→Rv2890c (RpsB) -(187)→Rv3240c |
0.3715 |
|
Rv2524c (Fas) -(464)→Rv2918c (GlnD) -(380)→Rv2890c -(187)→Rv3240c |
0.4833 |
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|
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The weighted score for each path is shown. The nodes upregulated by MAP drugs are indicated in bold typeface, while those that are upregulated by other drugs are underlined. The figures in parentheses indicate the edge weight; a lower edge weight indicates a higher confidence in the interaction. The edge weights range from 1 to 999. Lower edge weights are better. STRING scores range from 1 to 999. However, since edge weights are conventionally represented such that lower weights indicate better paths, the edge weights have been computed as 1000-STRING_score. |
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Raman and Chandra BMC Microbiology 2008 8:234 doi:10.1186/1471-2180-8-234 |
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