Analysis of the role of 13 major fimbrial subunits in colonisation of the chicken intestines by Salmonella enterica serovar Enteritidis reveals a role for a novel locus
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* Corresponding author: Debra J Clayton debra.clayton@bbsrc.ac.uk
- Equal contributors
1 Division of Microbiology, Institute for Animal Health, Compton, Berkshire, RG20 7NN, UK
2 Pathogen Genomics, Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK
3 School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, Leicestershire, LE12 5RD, UK
BMC Microbiology 2008, 8:228 doi:10.1186/1471-2180-8-228
Published: 18 December 2008Additional files
Additional file 1:
Organisation of the fimbrial operons of S. Enteritidis P125109. The image shows the gene organisation of each of the fimbrial operons, the Pfam domains within the fimbrial operons and the %GC content.
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Additional file 2:
Conservation of the nucleotide sequences of S. Enteritidis strain P125019 genes across sequenced strains of other S. enterica serovars. The table provides the percent nucleotide identity of each fimbrial gene in several serovars of Salmonella compared with S. Enteritidis P125109.
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Additional file 3:
3a. Dam methylase target sequence GATC within and proximal to S. Enteritidis P125109 fimbrial operons. 3b. Putative homo-polymeric tracts in the S. Enteritidis P125109 genome sequence. The tables indicate regions of potential phase variable targets.
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Additional file 4:
S. Enteritidis P125109 colonisation of Rhode Island Red Chickens at 1, 3 and 7 days post-infection. The graph shows the colonisation of S. Enteritidis P125109 at different organs within the chicken, at different times post-infection.
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